Whooping cough dynamics in Chile (1932–2010): disease temporal fluctuations across a north-south gradient

Whooping cough dynamics in Chile (1932-2010): disease temporal fluctuations across a north-south gradient.

BACKGROUND The spatial-temporal dynamics of Bordetella pertussis remains as a highly interesting case in infectious disease epidemiology. Despite large-scale vaccination programs in place for over 50 years around the world, frequent outbreaks are still reported in many countries. METHODS Here, we use annual time series of pertussis incidence from the thirteen different regions of Chile (1952-...

Seasonality and dynamics of whooping cough

Whooping cough (pertussis) dynamics provide an interesting disease ecology case study. Unlike other childhood diseases, the observed patterns of pertussis dynamics are found very diverse and are not easily captured by simple deterministic models. This has led to the current understanding that the disease dynamics can only be explained by adding stochasticity into the models. In this work, we de...

Whooping-Cough *

Following the isolation of the pertussis bacillus by Bordet and Gengou' in 1906, anticipation of methods of control of whoopingcough was inevitable. This discovery gave impetus to experimental and clinical investigations on various aspects of the whooping-cough problem. The isolation of the apparent causative agent, the introduction of new bacteriologic aids in early diagnosis, the transmission...

Whooping cough in adults.

During the 1970s whooping cough returned in Sweden after an absence of more than 10 years and is now seen in all age groups, During a three-year period 174 adults with culture-verified whooping cough were identified in Gothenburg. Most of the patients had typical symptoms with whooping attacks and often vomiting. The disease was long lasting but complications were rare. Physicians should be awa...

A Specific for Whooping Cough